DeCS Server - List Exact Term

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DeCS

Descriptor English:

Ribosomal Protein S6 Kinases

Descriptor Spanish:

Proteínas Quinasas S6 Ribosómicas

Descriptor Portuguese:

Proteínas Quinases S6 Ribossômicas

Synonyms English:

S6 Kinase

Tree Number:

Definition English:

A family of protein serine/threonine kinases which act as intracellular signalling intermediates. Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' top MRNAs. Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases.

See Related English:

History Note English:

2003(1998); use RIBOSOMAL PROTEIN S6 KINASES (NM) 1985-1997

Allowable Qualifiers English:

Record Number:

33474

Unique Identifier:

D019893

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